ID   TE 671
AC   CVCL_1756
SY   TE-671; TE671; TE671/RD
DR   BTO; BTO:0002605
DR   CLO; CLO_0009305
DR   CLO; CLO_0009317
DR   CLDB; cl4495
DR   CLDB; cl4496
DR   CLDB; cl4497
DR   ATCC; HTB-139
DR   BioSample; SAMN03151901
DR   ChEMBL-Cells; CHEMBL3307468
DR   ChEMBL-Targets; CHEMBL615012
DR   CLS; 300355
DR   Cosmic; 970091
DR   DSMZ; ACC-263
DR   DSMZCellDive; ACC-263
DR   ECACC; 89071904
DR   NCBI_Iran; C436
DR   PubChem_Cell_line; CVCL_1756
DR   Wikidata; Q54971989
RX   PubMed=892931;
RX   PubMed=2650908;
RX   PubMed=2911385;
RX   PubMed=2739733;
RX   PubMed=3335022;
RX   PubMed=11668190;
RX   PubMed=20143388;
RX   PubMed=24335698;
CC   Problematic cell line: Contaminated. Shown to be a RD derivative (PubMed=2650908; PubMed=2739733; PubMed=2911385; PubMed=20143388). Originally thought to originate from a 6 year old female patient with a medulloblastoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00101.
CC   Population: Caucasian.
CC   Doubling time: ~70-80 hours (DSMZ=ACC-263).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
CC   Discontinued: ATCC; HTB-139; true.
CC   Discontinued: DSMZ; ACC-263; true.
CC   Discontinued: ECACC; 89071904; true.
CC   Derived from sampling site: Pelvis; muscle.
ST   Source(s): ATCC; CLS; DSMZ; PubMed=11416159
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 13
ST   D16S539: 10,11
ST   D18S51: 13
ST   D19S433: 11,14
ST   D21S11: 28,29
ST   D2S1338: 22,23
ST   D3S1358: 15,17
ST   D5S818: 10,11
ST   D7S820: 8,12
ST   D8S1179: 11,15
ST   FGA: 20,21
ST   Penta D: 11,13
ST   Penta E: 12
ST   TH01: 9.3
ST   TPOX: 9
ST   vWA: 18
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1649 ! RD
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 29
RX   PubMed=892931; DOI=10.1002/ijc.2910200207;
RA   McAllister R.M., Isaacs H., Rongey R., Peer M., Au W., Soukup S.W.,
RA   Gardner M.B.;
RT   "Establishment of a human medulloblastoma cell line.";
RL   Int. J. Cancer 20:206-212(1977).
RX   PubMed=2650908; DOI=10.1093/carcin/10.5.899;
RA   Stratton M.R., Darling J.L., Pilkington G.J., Lantos P.L., Reeves B.R.,
RA   Cooper C.S.;
RT   "Characterization of the human cell line TE671.";
RL   Carcinogenesis 10:899-905(1989).
RX   PubMed=2911385; DOI=10.1038/337311c0;
RA   Stratton M.R., Reeves B.R., Cooper C.S.;
RT   "Misidentified cell.";
RL   Nature 337:311-312(1989).
RX   PubMed=2739733; DOI=10.1038/340106b0;
RA   Chen T.-R., Dorotinsky C., Macy M.L., Hay R.J.;
RT   "Cell identity resolved.";
RL   Nature 340:106-106(1989).
RX   PubMed=3335022;
RA   Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J.,
RA   Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.;
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
RX   PubMed=11668190; DOI=10.1177/002215540104901105;
RA   Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.;
RT   "Immunocytochemical analysis of cell lines derived from solid
RT   tumors.";
RL   J. Histochem. Cytochem. 49:1369-1378(2001).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
RX   PubMed=24335698; DOI=10.1093/neuonc/not202;
RA   An Q., Fillmore H.L., Vouri M., Pilkington G.J.;
RT   "Brain tumor cell line authentication, an efficient alternative to
RT   capillary electrophoresis by using a microfluidics-based system.";
RL   Neuro-oncol. 16:265-273(2014).