Cellosaurus logo
expasy logo

Cellosaurus Ramos.2G6.4C10 (CVCL_1646)

[Text version]
Cell line name Ramos.2G6.4C10
Synonyms RAMOS.2G6.4C10; Ramos-2G6-4C10; RAMOS-2G6-4C10; Ramos 2G6.4C10; Ramos 2G6 4C10; RAMOS2G64C10; Ramos.G6.C10; Ramos G6.C10
Accession CVCL_1646
Resource Identification Initiative To cite this cell line use: Ramos.2G6.4C10 (RRID:CVCL_1646)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Virology: EBV-negative.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (DepMap=ACH-002300).
Genome ancestry Source: PubMed=30894373

Origin% genome
African4.71
Native American43.61
East Asian, North3.64
East Asian, South0
South Asian0
European, North22.74
European, South25.29
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1923; Cosmic-CLP=910401

Markers:
AmelogeninX
CSF1PO10,11
D2S133820,23
D3S135814,15
D5S8187,12
D7S82011
D8S117913,16
D13S31713
D16S53910,13
D18S5115
D19S43314,15.2
D21S1130
FGA20,24
Penta D10,13
Penta E8,21
TH017,9.3
TPOX8,9
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=1698879; DOI=10.1016/0022-1759(90)90040-3
Siegel J.P., Mostowski H.S.
A bioassay for the measurement of human interleukin-4.
J. Immunol. Methods 132:287-295(1990)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-1923
Cell line databases/resources CLO; CLO_0008740
CLO; CLO_0037054
cancercelllines; CVCL_1646
Cell_Model_Passport; SIDM01247
Cosmic-CLP; 910401
DepMap; ACH-002300
LINCS_LDP; LCL-2027
Biological sample resources BioSample; SAMN03471265
Chemistry resources ChEMBL-Cells; CHEMBL3308341
ChEMBL-Targets; CHEMBL2366170
GDSC; 910401
PharmacoDB; Ramos2G64C10_1284_2019
PubChem_Cell_line; CVCL_1646
Encyclopedic resources Wikidata; Q54949208
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670358
Polymorphism and mutation databases Cosmic; 687851
Cosmic; 910401
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number36