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Cellosaurus MUTZ-2 (CVCL_1432)

[Text version]
Cell line name MUTZ-2
Synonyms MUTZ2; Mutz2; Menschliche Und Tierische Zellkulture-2
Accession CVCL_1432
Resource Identification Initiative To cite this cell line use: MUTZ-2 (RRID:CVCL_1432)
Comments Doubling time: ~47 hours (DSMZ=ACC-271); 48 hours (Note=In presence of supernatant of 5637 (Cellosaurus=CVCL_0126) cells) (PubMed=8667638).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:25657; BCORL1; Simple; p.Arg1420Ter (c.4258C>T); Zygosity=Unspecified (PubMed=21989985).
Disease Adult acute myeloid leukemia with maturation (NCIt: C7961)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-271

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,23
D3S135815,17
D5S81811,12
D7S82010,11
D8S117913,14
D13S3179,12
D16S53910,11
D18S5113,16.2
D19S43313
D21S1130,32.2
FGA21,26
Penta D11,12
Penta E11
TH019.3
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=8667638
Hu Z.-B., Ma W., Zaborski M., MacLeod R.A.F., Quentmeier H., Drexler H.G.
Establishment and characterization of two novel cytokine-responsive acute myeloid and monocytic leukemia cell lines, MUTZ-2 and MUTZ-3.
Leukemia 10:1025-1040(1996)

PubMed=9096695; DOI=10.1038/sj.leu.2400621
Drexler H.G., Zaborski M., Quentmeier H.
Thrombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines.
Leukemia 11:541-551(1997)

PubMed=10637496; DOI=10.1038/sj.leu.2401604
Drexler H.G., Fombonne S., Matsuo Y., Hu Z.-B., Hamaguchi H., Uphoff C.C.
p53 alterations in human leukemia-lymphoma cell lines: in vitro artifact or prerequisite for cell immortalization?
Leukemia 14:198-206(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=21989985; DOI=10.1182/blood-2011-05-356204; PMCID=PMC3228503
Li M., Collins R., Jiao Y.-C., Ouillette P., Bixby D., Erba H., Vogelstein B., Kinzler K.W., Papadopoulos N., Malek S.N.
Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia.
Blood 118:5914-5917(2011)

Cross-references
Cell line collections (Providers) DSMZ; ACC-271
Cell line databases/resources CLO; CLO_0007902
DSMZCellDive; ACC-271
Lonza; 1245
Biological sample resources BioSample; SAMN03473338
Encyclopedic resources Wikidata; Q54907099
Polymorphism and mutation databases Cosmic; 787461
Cosmic; 975280
Cosmic; 1281337
Cosmic; 2750854
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23