ID   MUTZ-2
AC   CVCL_1432
SY   MUTZ2; Mutz2; Menschliche Und Tierische Zellkulture-2
DR   CLO; CLO_0007902
DR   BioSample; SAMN03473338
DR   Cosmic; 787461
DR   Cosmic; 975280
DR   Cosmic; 1281337
DR   Cosmic; 2750854
DR   DSMZ; ACC-271
DR   DSMZCellDive; ACC-271
DR   Lonza; 1245
DR   Wikidata; Q54907099
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=8667638;
RX   PubMed=9096695;
RX   PubMed=10637496;
RX   PubMed=21989985;
CC   Doubling time: ~47 hours (DSMZ=ACC-271); 48 hours (Note=In presence of supernatant of 5637 (Cellosaurus=CVCL_0126) cells) (PubMed=8667638).
CC   Sequence variation: Mutation; HGNC; HGNC:25657; BCORL1; Simple; p.Arg1420Ter (c.4258C>T); Zygosity=Unspecified (PubMed=21989985).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): DSMZ=ACC-271
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 9,12
ST   D16S539: 10,11
ST   D18S51: 13,16.2
ST   D19S433: 13
ST   D21S11: 30,32.2
ST   D2S1338: 17,23
ST   D3S1358: 15,17
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   D8S1179: 13,14
ST   FGA: 21,26
ST   Penta D: 11,12
ST   Penta E: 11
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C7961; Adult acute myeloid leukemia with maturation
DI   ORDO; Orphanet_98834; Acute myeloblastic leukemia with maturation
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 23
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=8667638;
RA   Hu Z.-B., Ma W., Zaborski M., MacLeod R.A.F., Quentmeier H.,
RA   Drexler H.G.;
RT   "Establishment and characterization of two novel cytokine-responsive
RT   acute myeloid and monocytic leukemia cell lines, MUTZ-2 and MUTZ-3.";
RL   Leukemia 10:1025-1040(1996).
//
RX   PubMed=9096695; DOI=10.1038/sj.leu.2400621;
RA   Drexler H.G., Zaborski M., Quentmeier H.;
RT   "Thrombopoietin supports the continuous growth of cytokine-dependent
RT   human leukemia cell lines.";
RL   Leukemia 11:541-551(1997).
//
RX   PubMed=10637496; DOI=10.1038/sj.leu.2401604;
RA   Drexler H.G., Fombonne S., Matsuo Y., Hu Z.-B., Hamaguchi H.,
RA   Uphoff C.C.;
RT   "p53 alterations in human leukemia-lymphoma cell lines: in
RT   vitro artifact or prerequisite for cell immortalization?";
RL   Leukemia 14:198-206(2000).
//
RX   PubMed=21989985; DOI=10.1182/blood-2011-05-356204; PMCID=PMC3228503;
RA   Li M., Collins R., Jiao Y.-C., Ouillette P., Bixby D., Erba H.,
RA   Vogelstein B., Kinzler K.W., Papadopoulos N., Malek S.N.;
RT   "Somatic mutations in the transcriptional corepressor gene BCORL1 in
RT   adult acute myelogenous leukemia.";
RL   Blood 118:5914-5917(2011).
//