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Cellosaurus MP-CCS-SY (CVCL_0J33)

[Text version]
Cell line name MP-CCS-SY
Synonyms Miyazaki Pediatrics-Clear cell Sarcoma-SY
Accession CVCL_0J33
Resource Identification Initiative To cite this cell line use: MP-CCS-SY (RRID:CVCL_0J33)
Comments Population: Japanese.
Doubling time: 36 hours (PubMed=12072203).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Bone, left femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=12072203; PubMed=28745431).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 17-18Y
Category Cancer cell line
STR profile Source(s): PubMed=36959380

Markers:
AmelogeninX
CSF1PO9,12
D3S135817
D5S8189,12
D7S8208,13
D8S117913,14
D13S31711,12
D16S5399,11
D18S5114,25
D21S1130,32.2
FGA20,22
Penta D9,11
Penta E11,12
TH017,9.3
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=12072203; DOI=10.1016/S0165-4608(01)00641-0
Moritake H., Sugimoto T., Asada Y., Yoshida M.A., Maehara Y., Epstein A.L., Kuroda H.
Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene.
Cancer Genet. Cytogenet. 135:48-56(2002)

PubMed=28745431; DOI=10.1002/cam4.1130; PMCID=PMC5603837
Nakai T., Imura Y., Tamiya H., Yamada S., Nakai S., Yasuda N., Kaneko K., Outani H., Takenaka S., Hamada K., Myoui A., Araki N., Ueda T., Itoh K., Yoshikawa H., Naka N.
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma.
Cancer Med. 6:2121-2130(2017)

CLPUB00599
Sugimoto T., Kuroda H., Kuwahara Y., Katsumi Y., Misawa A., Moritake H., Hosoi H.
Cellular and molecular characteristics of established childhood soft-tissue sarcoma cell lines.
J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019)

PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623
Rasmussen S.V., Wozniak A., Lathara M., Goldenberg J.M., Samudio B.M., Bickford L.R., Nagamori K., Wright H., Woods A.D., Chauhan S., Lee C.-J., Rudzinski E.R., Swift M.K., Kondo T., Fisher D.E., Imyanitov E.N., Machado I., Llombart-Bosch A., Andrulis I.L., Gokgoz N., Wunder J.S., Moritake H., Nakamura T., Srinivasa G., Thway K., Jones R.L., Huang P.H., Berlow N.E., Schoffski P., Keller C.
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
Br. J. Cancer 128:1941-1954(2023)

Cross-references
Encyclopedic resources Wikidata; Q28726672
Sequence databases EGA; EGAD00001008611
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number13