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Cellosaurus SV80 (CVCL_0541)

[Text version]
Cell line name SV80
Synonyms SV-80; SV 80; SV-A clone 80; SV clone 80; Simian virus 80
Accession CVCL_0541
Resource Identification Initiative To cite this cell line use: SV80 (RRID:CVCL_0541)
Comments Problematic cell line: Probably misidentified. Said to originate from fibroblasts of the lung of a male black individual (CLS=300345), but in reality seems to be established from skin fibroblast of an adult female (strain A). Note that some papers have probably missasigned it to be from a Fanconi anemia patient.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
STR profile Source(s): CLS

Penta D9
Penta E11,12

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PubMed=14086148; DOI=10.1002/jcp.1030620305
Todaro G.J., Wolman S.R., Green H.
Rapid transformation of human fibroblasts with low growth potential into established cell lines by SV40.
J. Cell. Comp. Physiol. 62:257-265(1963)

PubMed=4288245; DOI=10.1126/science.153.3741.1252
Todaro G.J., Green H., Swift M.R.
Susceptibility of human diploid fibroblast strains to transformation by SV40 virus.
Science 153:1252-1254(1966)

PubMed=4359949; DOI=10.1128/JVI.12.4.711-720.1973
Benveniste R.E., Todaro G.J., Scolnick E.M., Parks W.P.
Partial transcription of murine type C viral genomes in BALB c cell lines.
J. Virol. 12:711-720(1973)

PubMed=4129832; DOI=10.1093/jnci/52.1.167
Todaro G.J., Meyer C.A.
Transformation assay for murine sarcoma viruses using a simian virus 40-transformed human cell line.
J. Natl. Cancer Inst. 52:167-171(1974)

PubMed=4370249; DOI=10.1016/0092-8674(74)90041-5
Henderson I.C., Livingston D.M.
Partial purification and characterization of the SV40 T antigen.
Cell 3:65-70(1974)

PubMed=174085; DOI=10.1073/pnas.72.12.4971
Stiles C.D., Desmond W. Jr., Sato G.H., Saier M.H. Jr.
Failure of human cells transformed by simian virus 40 to form tumors in athymic nude mice.
Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975)

Stiles C.D., Desmond W. Jr., Chuman L.M., Sato G.H., Saier M.H. Jr.
Growth control of heterologous tissue culture cells in the congenitally athymic nude mouse.
Cancer Res. 36:1353-1360(1976)

PubMed=68015; DOI=10.1002/ijc.2910190509
Flugel R.M., Crefeld T., Munk K.
Detection of SV40 T antigen with labelled antibodies: radioimmunoassay and autoradiography.
Int. J. Cancer 19:656-663(1977)

PubMed=6328024; DOI=10.1128/JVI.50.3.943-946.1984
Gruss C., Baumann E., Knippers R.
DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80.
J. Virol. 50:943-946(1984)

Cell line collections (Providers) ATCC; CRL-7725 - Discontinued
CLS; 300345
Cell line databases/resources MCCL; MCC:0000442
Encyclopedic resources Wikidata; Q54970989
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number15