ID   SV80
AC   CVCL_0541
SY   SV-80; SV 80; SV-A clone 80; SV clone 80; Simian virus 80
DR   MCCL; MCC:0000442
DR   ATCC; CRL-7725
DR   CLS; 300345
DR   Wikidata; Q54970989
RX   PubMed=68015;
RX   PubMed=174085;
RX   PubMed=1260760;
RX   PubMed=4129832;
RX   PubMed=4288245;
RX   PubMed=4359949;
RX   PubMed=4370249;
RX   PubMed=6328024;
RX   PubMed=14086148;
CC   Problematic cell line: Probably misidentified. Said to originate from fibroblasts of the lung of a male black individual (CLS=300345), but in reality seems to be established from skin fibroblast of an adult female (strain A). Note that some papers have probably missasigned it to be from a Fanconi anemia patient.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Discontinued: ATCC; CRL-7725; true.
ST   Source(s): CLS
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 9,13
ST   D18S51: 15,20
ST   D21S11: 28,30
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 10
ST   D8S1179: 11,15
ST   FGA: 21,27
ST   Penta D: 9
ST   Penta E: 11,12
ST   TH01: 9
ST   TPOX: 10,11
ST   vWA: 16
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 15
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RX   PubMed=68015; DOI=10.1002/ijc.2910190509;
RA   Flugel R.M., Crefeld T., Munk K.;
RT   "Detection of SV40 T antigen with labelled antibodies:
RT   radioimmunoassay and autoradiography.";
RL   Int. J. Cancer 19:656-663(1977).
//
RX   PubMed=174085; DOI=10.1073/pnas.72.12.4971;
RA   Stiles C.D., Desmond W. Jr., Sato G.H., Saier M.H. Jr.;
RT   "Failure of human cells transformed by simian virus 40 to form tumors
RT   in athymic nude mice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975).
//
RX   PubMed=1260760;
RA   Stiles C.D., Desmond W. Jr., Chuman L.M., Sato G.H., Saier M.H. Jr.;
RT   "Growth control of heterologous tissue culture cells in the
RT   congenitally athymic nude mouse.";
RL   Cancer Res. 36:1353-1360(1976).
//
RX   PubMed=4129832; DOI=10.1093/jnci/52.1.167;
RA   Todaro G.J., Meyer C.A.;
RT   "Transformation assay for murine sarcoma viruses using a simian virus
RT   40-transformed human cell line.";
RL   J. Natl. Cancer Inst. 52:167-171(1974).
//
RX   PubMed=4288245; DOI=10.1126/science.153.3741.1252;
RA   Todaro G.J., Green H., Swift M.R.;
RT   "Susceptibility of human diploid fibroblast strains to transformation
RT   by SV40 virus.";
RL   Science 153:1252-1254(1966).
//
RX   PubMed=4359949; DOI=10.1128/JVI.12.4.711-720.1973;
RA   Benveniste R.E., Todaro G.J., Scolnick E.M., Parks W.P.;
RT   "Partial transcription of murine type C viral genomes in BALB c cell
RT   lines.";
RL   J. Virol. 12:711-720(1973).
//
RX   PubMed=4370249; DOI=10.1016/0092-8674(74)90041-5;
RA   Henderson I.C., Livingston D.M.;
RT   "Partial purification and characterization of the SV40 T antigen.";
RL   Cell 3:65-70(1974).
//
RX   PubMed=6328024; DOI=10.1128/JVI.50.3.943-946.1984;
RA   Gruss C., Baumann E., Knippers R.;
RT   "DNA binding properties of a mutant T antigen from the simian virus
RT   40-transformed human cell line simian virus 80.";
RL   J. Virol. 50:943-946(1984).
//
RX   PubMed=14086148; DOI=10.1002/jcp.1030620305;
RA   Todaro G.J., Wolman S.R., Green H.;
RT   "Rapid transformation of human fibroblasts with low growth potential
RT   into established cell lines by SV40.";
RL   J. Cell. Comp. Physiol. 62:257-265(1963).
//