ID   SV80
AC   CVCL_0541
SY   SV-80; SV 80; SV-A clone 80; SV clone 80; Simian virus 80
DR   MCCL; MCC:0000442
DR   ATCC; CRL-7725
DR   CLS; 300345
DR   Wikidata; Q54970989
RX   PubMed=68015;
RX   PubMed=174085;
RX   PubMed=1260760;
RX   PubMed=4129832;
RX   PubMed=4288245;
RX   PubMed=4359949;
RX   PubMed=4370249;
RX   PubMed=6328024;
RX   PubMed=14086148;
CC   Problematic cell line: Probably misidentified. Said to originate from fibroblasts of the lung of a male black individual (CLS=300345), but in reality seems to be established from skin fibroblast of an adult female (strain A). Note that some papers have probably missasigned it to be from a Fanconi anemia patient.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Discontinued: ATCC; CRL-7725; true.
ST   Source(s): CLS=300345
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 9,13
ST   D18S51: 15,20
ST   D21S11: 28,30
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 10
ST   D8S1179: 11,15
ST   FGA: 21,27
ST   Penta D: 9
ST   Penta E: 11,12
ST   TH01: 9
ST   TPOX: 10,11
ST   vWA: 16
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 16
//
RX   PubMed=174085; DOI=10.1073/pnas.72.12.4971; PMCID=PMC388856;
RA   Stiles, Charles Dean
RA   Desmond, Walter Jr.
RA   Sato, Gordon Hisashi
RA   Saier, Milton H. Jr.
RT   "Failure of human cells transformed by simian virus 40 to form tumors
RT   in athymic nude mice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975).
//
RX   PubMed=1260760;
RA   Stiles, Charles Dean
RA   Desmond, Walter Jr.
RA   Chuman, Lorraine M.
RA   Sato, Gordon Hisashi
RA   Saier, Milton H. Jr.
RT   "Growth control of heterologous tissue culture cells in the
RT   congenitally athymic nude mouse.";
RL   Cancer Res. 36:1353-1360(1976).
//
RX   PubMed=4370249; DOI=10.1016/0092-8674(74)90041-5;
RA   Henderson, Isaac Craig
RA   Livingston, David Morse
RT   "Partial purification and characterization of the SV40 T antigen.";
RL   Cell 3:65-70(1974).
//
RX   PubMed=4359949; DOI=10.1128/JVI.12.4.711-720.1973; PMCID=PMC356689;
RA   Benveniste, Raoul E.
RA   Todaro, George J.
RA   Scolnick, Edward M.
RA   Parks, Wade P.
RT   "Partial transcription of murine type C viral genomes in BALB c cell
RT   lines.";
RL   J. Virol. 12:711-720(1973).
//
RX   PubMed=6328024; DOI=10.1128/JVI.50.3.943-946.1984; PMCID=PMC255757;
RA   Gruss, Claudia
RA   Baumann, Ernst
RA   Knippers, Rolf
RT   "DNA binding properties of a mutant T antigen from the simian virus
RT   40-transformed human cell line simian virus 80.";
RL   J. Virol. 50:943-946(1984).
//
RX   PubMed=4129832; DOI=10.1093/jnci/52.1.167;
RA   Todaro, George J.
RA   Meyer, Charlotte A.
RT   "Transformation assay for murine sarcoma viruses using a simian virus
RT   40-transformed human cell line.";
RL   J. Natl. Cancer Inst. 52:167-171(1974).
//
RX   PubMed=68015; DOI=10.1002/ijc.2910190509;
RA   Flugel, Rolf M.
RA   Crefeld, T.
RA   Munk, Klaus
RT   "Detection of SV40 T antigen with labelled antibodies:
RT   radioimmunoassay and autoradiography.";
RL   Int. J. Cancer 19:656-663(1977).
//
RX   PubMed=14086148; DOI=10.1002/jcp.1030620305;
RA   Todaro, George J.
RA   Wolman, Sandra R.
RA   Green, Howard
RT   "Rapid transformation of human fibroblasts with low growth potential
RT   into established cell lines by SV40.";
RL   J. Cell. Comp. Physiol. 62:257-265(1963).
//
RX   PubMed=4288245; DOI=10.1126/science.153.3741.1252;
RA   Todaro, George J.
RA   Green, Howard
RA   Swift, Michael R.
RT   "Susceptibility of human diploid fibroblast strains to transformation
RT   by SV40 virus.";
RL   Science 153:1252-1254(1966).
//