ID   SV80
AC   CVCL_0541
SY   SV-80; SV 80; SV-A clone 80; SV clone 80; Simian virus 80
DR   MCCL; MCC:0000442
DR   ATCC; CRL-7725
DR   CLS; 300345
DR   Wikidata; Q54970989
RX   PubMed=68015;
RX   PubMed=174085;
RX   PubMed=1260760;
RX   PubMed=4129832;
RX   PubMed=4288245;
RX   PubMed=4359949;
RX   PubMed=4370249;
RX   PubMed=6328024;
RX   PubMed=14086148;
CC   Problematic cell line: Probably misidentified. Said to originate from fibroblasts of the lung of a male black individual (CLS), but in reality seems to be established from skin fibroblast of an adult female (strain A). Note that some papers have probably missasigned it to be from a Fanconi anemia patient.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Discontinued: ATCC; CRL-7725; true.
ST   Source(s): CLS
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 9,13
ST   D18S51: 15,20
ST   D21S11: 28,30
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 10
ST   D8S1179: 11,15
ST   FGA: 21,27
ST   Penta D: 9
ST   Penta E: 11,12
ST   TH01: 9
ST   TPOX: 10,11
ST   vWA: 16
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 14
RX   PubMed=68015; DOI=10.1002/ijc.2910190509;
RA   Flugel R.M., Crefeld T., Munk K.;
RT   "Detection of SV40 T antigen with labelled antibodies:
RT   radioimmunoassay and autoradiography.";
RL   Int. J. Cancer 19:656-663(1977).
RX   PubMed=174085; DOI=10.1073/pnas.72.12.4971;
RA   Stiles C.D., Desmond W. Jr., Sato G.H., Saier M.H. Jr.;
RT   "Failure of human cells transformed by simian virus 40 to form tumors
RT   in athymic nude mice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975).
RX   PubMed=1260760;
RA   Stiles C.D., Desmond W. Jr., Chuman L.M., Sato G.H., Saier M.H. Jr.;
RT   "Growth control of heterologous tissue culture cells in the
RT   congenitally athymic nude mouse.";
RL   Cancer Res. 36:1353-1360(1976).
RX   PubMed=4129832; DOI=10.1093/jnci/52.1.167;
RA   Todaro G.J., Meyer C.A.;
RT   "Transformation assay for murine sarcoma viruses using a simian virus
RT   40-transformed human cell line.";
RL   J. Natl. Cancer Inst. 52:167-171(1974).
RX   PubMed=4288245; DOI=10.1126/science.153.3741.1252;
RA   Todaro G.J., Green H., Swift M.R.;
RT   "Susceptibility of human diploid fibroblast strains to transformation
RT   by SV40 virus.";
RL   Science 153:1252-1254(1966).
RX   PubMed=4359949; DOI=10.1128/JVI.12.4.711-720.1973;
RA   Benveniste R.E., Todaro G.J., Scolnick E.M., Parks W.P.;
RT   "Partial transcription of murine type C viral genomes in BALB c cell
RT   lines.";
RL   J. Virol. 12:711-720(1973).
RX   PubMed=4370249; DOI=10.1016/0092-8674(74)90041-5;
RA   Henderson I.C., Livingston D.M.;
RT   "Partial purification and characterization of the SV40 T antigen.";
RL   Cell 3:65-70(1974).
RX   PubMed=6328024; DOI=10.1128/JVI.50.3.943-946.1984;
RA   Gruss C., Baumann E., Knippers R.;
RT   "DNA binding properties of a mutant T antigen from the simian virus
RT   40-transformed human cell line simian virus 80.";
RL   J. Virol. 50:943-946(1984).
RX   PubMed=14086148; DOI=10.1002/jcp.1030620305;
RA   Todaro G.J., Wolman S.R., Green H.;
RT   "Rapid transformation of human fibroblasts with low growth potential
RT   into established cell lines by SV40.";
RL   J. Cell. Comp. Physiol. 62:257-265(1963).