• Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  

PubMed=2425939
Marsh W., Sicheri D., Center M.S.
Isolation and characterization of adriamycin-resistant HL-60 cells which are not defective in the initial intracellular accumulation of drug.
Cancer Res. 46:4053-4057(1986)

PubMed=2886122; DOI=10.1016/0006-291X(87)91560-9
McGrath T., Center M.S.
Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein.
Biochem. Biophys. Res. Commun. 145:1171-1176(1987)

PubMed=2573357; DOI=10.1016/0006-2952(89)90134-2
McGrath T., Latoud C., Arnold S.T., Safa A.R., Felsted R.L., Center M.S.
Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression.
Biochem. Pharmacol. 38:3611-3619(1989)