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Cellosaurus Fa2N-4 (CVCL_0267)

[Text version]
Cell line name Fa2N-4
Synonyms Fa2N4
Accession CVCL_0267
Resource Identification Initiative To cite this cell line use: Fa2N-4 (RRID:CVCL_0267)
Comments Group: Patented cell line.
From: MultiCell Technologies, Inc.; Woonsocket; USA.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-5566.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 12Y
Category Transformed cell line
Publications

PubMed=14722322; DOI=10.1124/jpet.103.061713
Mills J.B., Rose K.A., Sadagopan N., Sahi J., de Morais S.M.F.
Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line.
J. Pharmacol. Exp. Ther. 309:303-309(2004)

PubMed=18332078; DOI=10.1124/dmd.108.020677
Hariparsad N., Carr B.A., Evers R., Chu X.-Y.
Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
Drug Metab. Dispos. 36:1046-1055(2008)

Patent=US7566567
Liu J., Faris R.A.
Immortalized hepatocytes.
Patent number US7566567, 28-Jul-2009

Cross-references
Cell line databases/resources CLO; CLO_0037255
MCCL; MCC:0000158
Encyclopedic resources Wikidata; Q54833201
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number12