ID   Fa2N-4
AC   CVCL_0267
SY   Fa2N4
DR   CLO; CLO_0037255
DR   MCCL; MCC:0000158
DR   Wikidata; Q54833201
RX   Patent=US7566567;
RX   PubMed=14722322;
RX   PubMed=18332078;
CC   Group: Patented cell line.
CC   From: MultiCell Technologies, Inc.; Woonsocket; USA.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-5566.
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   12Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 12
//
RX   Patent=US7566567;
RA   Liu J., Faris R.A.;
RT   "Immortalized hepatocytes.";
RL   Patent number US7566567, 28-Jul-2009.
//
RX   PubMed=14722322; DOI=10.1124/jpet.103.061713;
RA   Mills J.B., Rose K.A., Sadagopan N., Sahi J., de Morais S.M.F.;
RT   "Induction of drug metabolism enzymes and MDR1 using a novel human
RT   hepatocyte cell line.";
RL   J. Pharmacol. Exp. Ther. 309:303-309(2004).
//
RX   PubMed=18332078; DOI=10.1124/dmd.108.020677;
RA   Hariparsad N., Carr B.A., Evers R., Chu X.-Y.;
RT   "Comparison of immortalized Fa2N-4 cells and human hepatocytes as in
RT   vitro models for cytochrome P450 induction.";
RL   Drug Metab. Dispos. 36:1046-1055(2008).
//