Cellosaurus logo
expasy logo

Cellosaurus CTLL-2 (CVCL_0227)

[Text version]
Cell line name CTLL-2
Synonyms CTLL 2; CTLL2; CTLL(2)
Accession CVCL_0227
Resource Identification Initiative To cite this cell line use: CTLL-2 (RRID:CVCL_0227)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Characteristics: IL2 dependent.
Doubling time: 24 hours (PubMed=145543).
Cell type: T-cell; CL=CL_0000084.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_KS71 (CellSensor irf1-bla CTLL-2)CVCL_6829 (CT.EV)CVCL_D100 (CTL44)
CVCL_YU23 (CTLL-2 NF-kappaB)CVCL_9786 (CTLL-20)
Category Transformed cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-117
Mouse STR 1-219,20
Mouse STR 2-115,16
Mouse STR 3-214
Mouse STR 4-220.3
Mouse STR 5-517,18
Mouse STR 6-418,19
Mouse STR 6-717,20
Mouse STR 7-126.2
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-117
Mouse STR 13-116
Mouse STR 15-322.3,23.3
Mouse STR 17-214,15
Mouse STR 18-316
Mouse STR 19-213,14
Mouse STR X-128,29

Run an STR similarity search on this cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=CTLL-2
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-67.html
Publications

PubMed=145543; DOI=10.1038/268154a0
Gillis S., Smith K.A.
Long term culture of tumour-specific cytotoxic T cells.
Nature 268:154-156(1977)

PubMed=9619491; DOI=10.1046/j.1440-1711.1998.00733.x
Weston L., Geczy A., Farrell C.
A convenient and reliable IL-2 bioassay using frozen CTLL-2 to improve the detection of helper T lymphocyte precursors.
Immunol. Cell Biol. 76:190-192(1998)

PubMed=9744750; DOI=10.1016/S0022-1759(98)00065-9
Winandy M., Lewalle P., Deneys V., Ferrant A., De Bruyere M.
Improved IL-2 detection for determination of helper T lymphocyte precursor frequency in limiting dilution assay.
J. Immunol. Methods 215:81-94(1998)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections (Providers) ATCC; TIB-214
BCRC; 60376
BCRJ; 0281 - Discontinued
CLS; 400482
DSMZ; ACC-27 - Discontinued
ECACC; 93042610
ICLC; AL00003
NCBI_Iran; C538
RCB; RCB0637
Cell line databases/resources CLO; CLO_0002636
CLO; CLO_0050181
MCCL; MCC:0000115
CLDB; cl925
CLDB; cl4995
CCRID; 1102MOU-NIFDC00051
CCRID; 3101MOUGNM4
DSMZCellDive; ACC-27
Lonza; 1012
Anatomy/cell type resources BTO; BTO_0001482
Biological sample resources BioSample; SAMN11397659
Encyclopedic resources Wikidata; Q54814742
Experimental variables resources EFO; EFO_0002821
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number28