Description |
A hypodiploid cell line, from lung, metastatic site, pleural affusion carcinoma, held at ATCC. Karyotyped in collaboration with the Sanger Institute.
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Notable Features |
Hypodiploid with 10 structural rearrangements involving chromosomes 2, 3, 5, 8, 9, 11, 12, 13, 14, 15, 16, 18, 21, losses of chromosomes 4, 5q, 8, 9p, 10 and gain of chromosome 20. Five of the rearrangements are simple non-reciprocal translocations, one is a complex dicentric and one i(15q). Double minutes were observed in some cells involving chromosomes 3, 5, 6.
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42 (42-46), XY, 1x2, der(2)ins(2;12)(q;?), dic(2;12;2;21), 3x1, der(3)t(3;8), 4x1, 5x1, der(5)del(5)(q11-qter)x2, 6x2, 7x2, 8x1, 9x1, der(9)del(9)(p12-pter), 10x1, 11x1, der(11)t(11:?)(hsr11)hsr(12)hsr(?), 12x1, der(12)t(11;12), 13x1, 14x2, der(14)t(12;14), i(15q), 16x2, 17x2, 18x1, der(18)t(13;18)(q13-q14;q22), 19x2, 20x3, 21x2, 22x2, dmin
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