Molecular Cytogenetics of Common Epithelial Cancers > Lung Carcinoma cell lines > NCI-H2126

NCI-H2126   [Cellosaurus entry CVCL_1532]

Lung Cancer Cell Line


A hypotriploid cell line from metastatic site, pleural effusion adenocarcinoma, held at ATCC. Karyotyped in collaboration with the Sanger Institute.

Notable Features

Hypotriploid, highly rearranged cell line with 22 structural abnormalities, involving chromosomes 1, 2, 3, 5, 6, 7, 9, 12, 13, 14, 17, 18, 19, some of them complex, losses of chromosomes 6, 8, 10, 11, 15, 17, Y; gains of 20 and 22. Some cells contain double minutes (DM) involving chromosomes 1 and 11.

Representative SKY Karyotype

72(72-77) XX, -Y, i(1q), ider(1)(p10)t(1;15), der(1)del(1)(p10-pter), 2x3, der(2)t(2;X), 3x2, der(3)t(3;15)(p10-11;q), 4x3, der(5)del(5)x2, der(5)t(5;22)x2, der(5?)t(5;12?), 6x1, der(6)t(6;7), der(6)del(6)(q11-qter), 7x3, der(7)t(7;14), der(7)t(5;7), 8x2, 9x1, der(9)t(9;12;11)x2, der(9)del(9), der(10)del(10), 11x2, 12x2, der(12)t(1;12), 13x2, der(13)t(13;5;?)x2, der(14)t(14;?;14), der(5)t(5;?;14), der(14)t(14; 17), 15x1, 16x3, 17x2, 18x1, der(18)t(8;18)x2, 19x3, der(19)t(1;19)x2, ider(19)(q10)t(1;19), 20x5, 21x3, 22x4


Additional Information  



Lung Cancer Cell Lines