NCI-H2087   [Cellosaurus entry CVCL_1524]

Lung Cancer Cell Line

A hyperdiploid cell line from lung, metastatic site, lymph node adenocarcinoma, held at ATCC. Karyotyped in collaboration with the Sanger Institute.

Hyperdiploid, highly rearranged with 21 clonal structural abnormalities, involving chromosomes 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 13, 14, 15, 16, 19, 20, some of them complex, losses of chromosomes 4, 18, 19, 21, 22; partial gain of 5, 11, some cells have double minutes. 

49(42-49), X, Y, 1x1, der(1)t(1;11)(q31-32;q13), der(1;15)(q10;q10), 2x2, der(2)t(2;3), 3x1, der(3)t(3;21)(p21;q ), 4x1, 5x2, i(5p), der(5?)t(2;5), der(5?)t(5q;7), 6x2, der(6)t(6;7), 7x1, der(7)del(7), 8x1, der(8)t(12;8;1), der(8)t(18;8;20), 9x1, der(9)t(9q;4;3), der(9)del(9), 10x1, der(10)t(3;10)(?;q24-25), der(10)del(10) ^a, 11x2, der(11)t(7;11)(?;q22-24), 12x1, der(13;14)(q10;q10)x2, 14x1, , 15x1, 16x2, 17x2, 18x1, 19x1, der(19)t(15;19), 20x1, der(20)t(5/16?;20), der(20)t(4;20), 21x1, 22x1, der(22)t(22;5;3), dmin ^a

 ^a in less than 50% of cells

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Lung Cancer Cell Lines