Publication number |
CLPUB00745 |
Authors |
Harris N.S. |
Title |
Characterization of a polypeptide factor that inhibits the growth of a human breast cancer line in vitro. |
Citation |
Thesis MD (1988); University of Cape Town; Cape Town; South Africa |
Web pages |
https://hdl.handle.net/11427/25852 |
Abstract |
This thesis concerns a melanoma-derived growth regulatory factor that
inhibited proliferation of several malignant human cell lines, and, in
particular, a line designated UCT-BR-1, which was derived from a human
breast cancer metastasis. The work is presented in four chapters. Chapter
1 provides a review of the relevant literature at the time of writing;
Chapters 2 and 3 describe the experimental work that was done; and in
Chapter 4 I discuss the implications of my results for current and future
work in growth factors. Experimental results are presented as Charts
(which may be Figures or Tables) and the methods and experimental
protocols that I used are described in the Chart legends and not in the
main text of the thesis. The Appendix contains details of the tissue
culture techniques and descriptions of the cell lines that were used.
Sources of the various laboratory materials as well as the methods that
were employed for the more routine procedures are also described in the
appendix.
|
Cell lines |
CVCL_A0LF; Bowes/sf CVCL_B1D6; UCT-Br 1 CVCL_A0LD; UCT-Ca 2 CVCL_A0LE; UCT-Sq 1 |