| Publication number |
CLPUB00743 |
|---|
| Authors |
Monroy-Garcia A., Rangel-Corona R., Rocha-Zavaleta L., Trejo-Becerril C., Ramirez-Gaytan J.L., Martinez-Perez R.D., Weiss-Steider B. |
|---|
| Title |
Desmoglein-1 contents and location of seven cell lines of normal cervix uteri and uterine cervix cancer. |
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| Citation |
Rev. Mex. Oncol. 7:69-76(1992) |
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| Web pages |
https://www.researchgate.net/publication/312969093 |
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| Abstract |
In order to determine whether the cell strains obtained from seven
cervical biopsies (five from cervical cancers and two from normal cervical
tissue) arose from epithelial tissue, the presence of desmoglein-1 (DG-1)
was evaluated using a polyclonal antibody against desmoglein-1 (anti-DG-1).
Although some strains had a typical fibroblast morphology, all were
positive for anti-DG-1. In consequence we assumed that all strains
consisted of epithelial cells. On the other hand our results showed that
cells from biopsies taken from patients with more advanced tumors
presented lower levels of DG-1 than cells from patients in early stages. A
discussion is provided as to whether these differences in DG-1 content can
be related to the metastatic properties of the tumor.
|
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| Cell lines |
CVCL_5121; CaLo CVCL_5140; INBL |
|---|
