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Cellosaurus publication CLPUB00720

Publication number CLPUB00720
Authors Greene A.E., Mulivor R.A.
Title 1986/1987 catalog of cell lines. NIGMS human genetic mutant cell repository. 13th edition. October 1986.
Citation (In) Institute for Medical Research (Camden, N.J.) NIH 87-2011; pp.1-549; National Institutes of Health; Bethesda (1986)
Web pages https://books.google.ch/books?id=fqEIAAAAIAAJ
Abstract Since its inception in 1972, the Human Genetic Mutant Cell Repository has processed more than 7,000 submitted cell cultures, tissue biopsies, and peripheral blood specimens and provided more than 35,000 cell cultures to investigators. These activities have resulted in a worldwide reputation for excellent, well characterized, thoroughly documented, and contaminant- free cell cultures. The thirteenth edition of the catalog contains 154 new listings bringing the total to 3,744 cell cultures. Special new additions to this edition of the catalog are 70 lymphoblastoid cultures obtained from a multigeneration maturity onset diabetes of the young pedigree. This family consists of a large number of affected, at risk and normal individuals and should be useful to investigators interested in gene mapping experiments. The HLA histocompatibility type cell culture collection was expanded by the addition of thirteen new lymphoblastoid cultures established from children of consanguineous parents. Lymphoblastoid cultures established from eight members of a family with Pelizaeus-Merzbacher disease and three patients with hemophilia B are also new additions to the catalog. Appendix D which presents the diagrammatic representation of chromosomally aberrant cell cultures depicting balanced translocations and unbalanced chromosomal aberrations resulting in specific chromo some segments (whole or part) being present in single, triple or greater dosages has been updated in this edition. On February 1, 1986 the name of the Institute for Medical Research was changed to the Coriell Institute for Medical Research in honor of its founder, Dr. Lewis L. Coriell, who retired in 1985. Dr. Coriell provided leadership , guidance and dedication to the Institute since its beginning in 1953. He was the Principal Investigator of the NIGMS Human Genetic Mutant Cell Repository from its inception in 1972 till December 1983. Dr. Coriell's keen knowledge of the science of cell culture and his sense of what a cell repository should be guided the NIGMS Repository to its position as a major national resource for the study of human genetics.
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