| Publication number |
CLPUB00713 |
|---|
| Authors |
Stautner C.A. |
|---|
| Title |
Mitochondrial function in cellular models of idiopathic Parkinson's disease. |
|---|
| Citation |
Thesis PhD (2018); Technischen Universitat Munchen; Munich; Germany |
|---|
| Web pages |
https://mediatum.ub.tum.de/?id=1435947http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20181012-1435947-1-4 |
|---|
| Abstract |
Bioenergetic disturbances are a hallmark of neurodegenerative diseases, in
particular of Parkinson's disease (PD). This thesis concerns itself with a
cohort of idiopathic PD patients and matched controls collected by the
Bavarian ForiPS consortium. Induced pluripotent stem cells (iPSCs) and
their neuronal derivatives were established and analyzed for their
bioenergetic properties. Results shed new light on iPSCs as disease model
system and bioenergetic deficiencies in Parkinson's disease and integrate
well in existing research.
|
|---|
| Cell lines |
View cell lines |
|---|
