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Cellosaurus publication CLPUB00609

Publication number CLPUB00609
Authors Digneffe C., Cormont F., Platteau B., Bazin H.
Title Fusion cell lines.
Citation (In book chapter) Rat hybridomas and rat monoclonal antibodies; Bazin H. (eds.); pp.69-74; CRC Press; Boca Raton; USA (1990)
Abstract There are many fusion cell lines currently utilized for monoclonal antibody-secreting hybridoma production. They are all derived from mouse, rat, or human cell lines. Human hybridomas are still at an early stage of development. On the contrary, both mouse and rat systems are widely used. The mouse system is historically the first to have been developed by Kohler and Milstein as a method for the production of monoclonal antibodies of predefined specificity, and several mouse fusion lines are available. However, the rat system has been reported to have definite advantages at least in some circumstances.
Cell lines CVCL_7675; IR983F
CVCL_4342; Y3-Ag 1.2.3
CVCL_8984; YB2/0