Publication number |
CLPUB00609 |
Authors |
Digneffe C., Cormont F., Platteau B., Bazin H. |
Title |
Fusion cell lines. |
Citation |
(In book chapter) Rat hybridomas and rat monoclonal antibodies; Bazin H. (eds.); pp.69-74; CRC Press; Boca Raton; USA (1990) |
Abstract |
There are many fusion cell lines currently utilized for monoclonal
antibody-secreting hybridoma production. They are all derived from mouse,
rat, or human cell lines. Human hybridomas are still at an early stage of
development. On the contrary, both mouse and rat systems are widely used.
The mouse system is historically the first to have been developed by
Kohler and Milstein as a method for the production of monoclonal
antibodies of predefined specificity, and several mouse fusion lines are
available. However, the rat system has been reported to have definite
advantages at least in some circumstances.
|
Cell lines |
CVCL_7675; IR983F CVCL_4342; Y3-Ag 1.2.3 CVCL_8984; YB2/0 |