| Publication number |
CLPUB00569 |
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| Authors |
Dickman P.S., Tsokos M., Triche T.J. |
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| Title |
Biology of rhabdomyosarcoma: cell culture, xenografts, and animal models. |
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| Citation |
(In book chapter) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer H.M., Ruymann F.B., Pochedly C.E. (eds.); pp.49-88; CRC Press; Boca Raton; USA (1991) |
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| Abstract |
Experimental models of human neoplasms have provided valuable tools for
exploring numerous biological and clinical features of tumors.
Rhabdomyosarcoma (RMS) has been studied using tumors induced in
experimental animals, in cell lines derived from such tumors, in cell
lines developed from human tumors, and in xenografts in athymic or nude
mice using both human primary tumors and tumor cell lines. In this chapter
the authors will describe these models, and information derived from the
various tumor systems will be reviewed. Special emphasis is placed on
biological and molecular biological findings, as well as using clinical or
therapeutic relevance of studies of human cell lines and xenografts.
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| Cell lines |
View cell lines |
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