Publication number |
CLPUB00325 |
Authors |
Vo N.T.K., Sansom B., Kozlowski E., Bloch S., Lee L.E.J. |
Title |
Development of a permanent cell line derived from fathead minnow testis and its applications in environmental toxicology. |
Citation |
Bull. Mt Desert Isl. Biol. Lab. Salisb. Cove Maine 49:83-86(2010) |
Web pages |
https://legacy.wlu.ca/docsnpubs_detail.php?grp_id=603&doc_id=42154 |
Abstract |
Fathead minnow (Pimephales promelas) is a widely used aquatic vertebrate
model organism used extensively in toxicology both for regulatory testing
and research. Fathead minnows are especially important in the study of
environmental endocrine disruptors (EED's) and cell lines derived from
these organisms are being sought for ecotoxicological studies. In this
study, we report on a newly established epithelial cell line from fathead
minnow testis (FHMT-W1) and on their applicability for cytotoxicological
studies. These cells could be useful for understanding mechanisms of
testicular cell growth and differentiation in fathead minnow species as
well as in toxicity response in aquatic animals.
|
Cell lines |
CVCL_L018; FHMT-W1 |