| Abstract |
A cell line with continuous multiplication has been established from
ovarian tissue of Lepidoptera B. mori chrysalids. This cell line which has
been remarkably stabilized during numerous subcultures, is at the basis of
several in vitro pathological studies. In virology it now enables the
ultrastructural study of the chronology of pathogenesis to be carried out
in the baculovirus of nuclear polyhedrosis, the reovirus of cytoplasmic
polyhedrosis and the densovirus. It is also used for studies on the action
of toxic substances produced by entomopathogenic fungi, on the cultivated
cells as well as on the antiviral action of these substances on in vitro
multiplied viruses. Necently, it enabled the obtention and the analysis of
genetic recombinants of Baculovirus.
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