| Publication number |
CLPUB00074 |
|---|
| Authors |
Kurayama H., Ogata S., Nanba M., Ikeguchi S., Takaoka T., Shida S. |
|---|
| Title |
Establishment of a new cell line secreting colony stimulating factor and growth inhibiting factor from metastatic lymph nodes of a rat. |
|---|
| Citation |
Dokkyo J. Med. Sci. 13:9-13(1986) |
|---|
| Web pages |
https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=200902071698605541 |
|---|
| Abstract |
A new tissue culture cell line (LYM-1) has been established from
metastatic lymph nodes of a rat, bearing colon cancer. The cancer was
produced by N-methyl-N'-nitro-N-nitrosourea treatment. Morphological
appearance of LYM-1 cells suggests that this cell line might consist of a
mixed population of fibroblast-and histiocyte-like cells. LYM-1 cells
released two kinds of factors; colony-stimulating factor and growth-
inhibiting factor. The colonystimulating factor stimulated the formation
of macrophage and granulocyte colonies. The growth-inhibiting factor
inhibited the growth of JTC-16 cells derived from the rat ascites hepatoma
AH-7974.
|
|---|
| Cell lines |
CVCL_4859; LYM-1 |
|---|
