| Abstract |
In the course of our survey to find avian species with distinguishable
nuclear and chromosomal morphology we found that cultures from embryonic
domestic geese (Anser anser) were unusual in that senescence occurred much
later than in other avian species. Consequently, we decided to discover
when in a series of continuous passages senescence might occur for goose
cells under the same clonal culture conditions which were known to permit
only fifty doublings of chicken cells. Two of the three cell lines became
senescent after only 65 generations, but one, CGBQ, has continued to grow
well past 100 cell generations in culture. This has been considered
indicative of the form of an "established cell line".
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