| Cell line name |
M14-CDM |
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| Synonyms |
M14 CDM; M14-Chemically Defined Medium |
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| Accession |
CVCL_ZZ71 |
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| Resource Identification Initiative |
To cite this cell line use: M14-CDM (RRID:CVCL_ZZ71) |
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| Comments |
Group: Serum/protein free medium cell line.
Population: Caucasian.
Derived from site: Metastatic; Right buttock, hypodermis; UBERON=UBERON_0013691+UBERON_0002072. |
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| Sequence variations |
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.150+2T>C (IVS1+2T>C); ClinVar=VCV000406712; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.455insCdel26; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Amelanotic melanoma (NCIt: C3802) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1395 (M14) |
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| Sex of cell |
Male |
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| Age at sampling |
33Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=1260767
Chee D.O., Boddie A.W. Jr., Roth J.A., Holmes E.C., Morton D.L.
Production of melanoma-associated antigen(s) by a defined malignant melanoma cell strain grown in chemically defined medium.
Cancer Res. 36:1503-1509(1976) PubMed=6386801; DOI=10.1016/S0021-9258(18)90807-0
Bumol T.F., Walker L.E., Reisfeld R.A.
Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans.
J. Biol. Chem. 259:12733-12741(1984) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_ZZ71
|
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| Encyclopedic resources |
Wikidata; Q102114489
|
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| Entry history |
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| Entry creation | 29-Oct-2020 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 8 |
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