ID   MCF-7/BCRP
AC   CVCL_ZZ40
SY   MCF-7/Bcrp
DR   cancercelllines; CVCL_ZZ40
DR   Wikidata; Q102114505
RX   PubMed=15695404;
CC   Population: Caucasian.
CC   Characteristics: Transfected with a Myc-tagged ABCG2/BCRP.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 74; ABCG2.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 10-09-24; Version: 7
//
RX   PubMed=15695404;
RA   Imai Y., Ishikawa E., Asada S., Sugimoto Y.;
RT   "Estrogen-mediated post transcriptional down-regulation of breast
RT   cancer resistance protein/ABCG2.";
RL   Cancer Res. 65:596-604(2005).
//