Cellosaurus cell line 2SOD1-4 (CVCL

Cross-references
Cell line name	2SOD1-4
Accession	CVCL_ZY48
Resource Identification Initiative	To cite this cell line use: 2SOD1-4 (RRID:CVCL_ZY48)
Comments	Population: Japanese. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:11179; SOD1; Simple; p.His47Arg (c.140A>G) (H46R); ClinVar=VCV000014764; Zygosity=Unspecified (PubMed=30127392).
Disease	Amyotrophic lateral sclerosis 1 (NCIt: C168749) Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_ZY47 ! 2SOD1-1
Sex of cell	Female
Age at sampling	45Y
Category	Induced pluripotent stem cell
Publications	PubMed=30127392; DOI=10.1038/s41591-018-0140-5 Fujimori K., Ishikawa M., Otomo A., Atsuta N., Nakamura R., Akiyama T., Hadano S., Aoki M., Saya H., Sobue G., Okano H. Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent. Nat. Med. 24:1579-1589(2018)
Encyclopedic resources	Wikidata; Q102113438
Entry history
Entry creation	29-Oct-2020
Last entry update	19-Dec-2024
Version number	6