Cellosaurus TC-1/dB2m (CVCL_ZX01)
| Cell line name | TC-1/dB2m |
|---|---|
| Accession | CVCL_ZX01 |
| Resource Identification Initiative | To cite this cell line use: TC-1/dB2m (RRID:CVCL_ZX01) |
| Comments | Characteristics: Irreversible MHC class I downregulation and has a reduced proliferation rate and tumor growth (PubMed=31638243). Doubling time: 27.9 hours (PubMed=31638243). Knockout cell: Method=CRISPR/Cas9; MGI; MGI:88127; B2m. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val). Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Epithelial cell; CL=CL_0000066. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6. |
| Hierarchy | Parent: CVCL_4699 (TC-1 [Mouse lung]) |
| Sex of cell | Sex unspecified |
| Age at sampling | Age unspecified |
| Category | Transformed cell line |
| Publications | PubMed=31638243; DOI=10.3892/or.2019.7356 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q102114971 |
| Entry history | |
| Entry creation | 29-Oct-2020 |
| Last entry update | 19-Dec-2024 |
| Version number | 10 |