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Cellosaurus SW1990/GEM (CVCL_ZW98)

[Text version]
Cell line name SW1990/GEM
Accession CVCL_ZW98
Resource Identification Initiative To cite this cell line use: SW1990/GEM (RRID:CVCL_ZW98)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1723 (SW1990)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=17217822; DOI=10.3760/j.issn.0529-5815.2006.19.016
Bu G.-B., Zhao Y.-P., Chen G., Zhang T.-P., Li L.-J., Wu Y.-D.
Expression and significance of GCS gene in human pancreatic cancer cell SW1990 and its drug-resistant sublines.
Zhonghua Wai Ke Za Zhi 44:1342-1344(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZW98
Encyclopedic resources Wikidata; Q102114956
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number7