ID   HuH-7-END
AC   CVCL_ZW90
SY   HuH7-HDV-Env-NTCP clone B1
DR   cancercelllines; CVCL_ZW90
DR   Wikidata; Q102114176
RX   PubMed=31292511;
CC   Population: Japanese.
CC   Characteristics: Transfected with pJC126, a plasmid harboring a 1.1-fold cDNA copy of the HDV antigenome.
CC   Virology: Persistently replicates and secretes hepatitis delta virus (HDV).
CC   Sequence variation: Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 10905; SLC10A1.
CC   Transfected with: UniProtKB; P03138; Hepatitis B virus genotype D subtype ayw envelope protein (HBsAg).
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0336 ! Huh-7
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 05-10-23; Version: 7
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RX   PubMed=31292511; DOI=10.1038/s41598-019-46493-1;
RA   Ni Y., Zhang Z.-F., Engelskircher L., Verch G., Tu T., Lempp F.A.,
RA   Urban S.;
RT   "Generation and characterization of a stable cell line persistently
RT   replicating and secreting the human hepatitis delta virus.";
RL   Sci. Rep. 9:10021-10021(2019).
//