ID   iHFK-shNrf2#2
AC   CVCL_ZW75
DR   Wikidata; Q102114209
RX   PubMed=31319135;
CC   Knockout cell: Method=shRNA knockdown; HGNC; HGNC:7782; NFE2L2.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_ZW73 ! iHFK-shNeg
OI   CVCL_ZW74 ! iHFK-shNrf2#1
OI   CVCL_ZW76 ! iHFK-shNrf2#3
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 29-10-20; Last updated: 14-08-25; Version: 10
//
RX   PubMed=31319135; DOI=10.1016/j.tiv.2019.104602;
RA   Choi, Moonju
RA   Park, Minkyung
RA   Lee, Sungjin
RA   Lee, Jeong Woo
RA   Choi, Won Jun
RA   Lee, Choongho
RT   "Establishment of Nrf2-deficient HaCaT and immortalized primary human
RT   foreskin keratinocytes and characterization of their responses to
RT   ROS-induced cytotoxicity.";
RL   Toxicol. In Vitro 61:104602.1-104602.12(2019).
//