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Cellosaurus KE (CVCL_ZV52)

[Text version]
Cell line name KE
Accession CVCL_ZV52
Resource Identification Initiative To cite this cell line use: KE (RRID:CVCL_ZV52)
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; c.(2062_3114)ins?; Zygosity=Unspecified (PubMed=10698499).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly36Glu (c.107G>A); ClinVar=VCV000486972; Zygosity=Unspecified (PubMed=9090379).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=2964515; DOI=10.1007/BF00148389
Yung W.-K.A., Steck P.A., Kelleher P.J., Moser R.P., Rosenblum M.G.
Growth inhibitory effect of recombinant alpha and beta interferon on human glioma cells.
J. Neurooncol. 5:323-330(1987)

PubMed=9070656; DOI=10.1038/sj.onc.1200925
Ligon A.H., Pershouse M.A., Jasser S.A., Yung W.-K.A., Steck P.A.
Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma.
Oncogene 14:1075-1081(1997)

PubMed=9090379; DOI=10.1038/ng0497-356
Steck P.A., Pershouse M.A., Jasser S.A., Yung W.-K.A., Lin H., Ligon A.H., Langford L.A., Baumgard M.L., Hattier T., Davis T., Frye C., Hu R., Swedlund B., Teng D.H.-F., Tavtigian S.V.
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.
Nat. Genet. 15:356-362(1997)

PubMed=10698499; DOI=10.1038/sj.onc.1203409
Ciesielski M.J., Fenstermaker R.A.
Oncogenic epidermal growth factor receptor mutants with tandem duplication: gene structure and effects on receptor function.
Oncogene 19:810-820(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZV52
Encyclopedic resources Wikidata; Q98126819
Polymorphism and mutation databases Cosmic; 850739
Cosmic; 1014069
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7