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Cellosaurus UCD4 (CVCL_ZV41)

[Text version]
Cell line name UCD4
Accession CVCL_ZV41
Resource Identification Initiative To cite this cell line use: UCD4 (RRID:CVCL_ZV41)
Comments Characteristics: Established from a patient-derived xenograft.
Characteristics: ER/PR-positive and ERBB2-negative.
Doubling time: 95.9 hours, 89.3 hours (Note=With 17-beta-estradiol) (PubMed=32576280).
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys585Asnfs*3 (c.1755_1759delGAAAA); ClinVar=VCV000037754; Zygosity=Unspecified (PubMed=32576280).
  • Mutation; HGNC; HGNC:3467; ESR1; Simple; p.Asp538Gly (c.1613A>G); Zygosity=Unspecified (PubMed=32576280).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 68Y
Category Cancer cell line
Publications

PubMed=32576280; DOI=10.1186/s13058-020-01300-y; PMCID=PMC7310532
Finlay-Schultz J., Jacobsen B.M., Riley D., Paul K.V., Turner S., Ferreira-Gonzalez A., Harrell J.C., Kabos P., Sartorius C.A.
New generation breast cancer cell lines developed from patient-derived xenografts.
Breast Cancer Res. 22:68.1-68.12(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZV41
Encyclopedic resources Wikidata; Q98133838
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number8