Cellosaurus cell line XP22BR (CVCL

Cross-references
Cell line name	XP22BR
Synonyms	Xeroderma Pigmentosum 22 BRighton
Accession	CVCL_ZV09
Resource Identification Initiative	To cite this cell line use: XP22BR (RRID:CVCL_ZV09)
Comments	Population: Middle Eastern. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:12816; XPC; Simple; p.Arg220Ter (c.658C>T); ClinVar=VCV000550020; Zygosity=Homozygous (PubMed=26884178).
Disease	Xeroderma pigmentosum, complementation group C (NCIt: C114770) Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	38Y
Category	Finite cell line
Publications	PubMed=26884178; DOI=10.1073/pnas.1519444113; PMCID=PMC4780618 Fassihi H., Sethi M., Fawcett H., Wing J.F., Chandler N., Mohammed S., Craythorne E., Morley A.M.S., Lim R.-X., Turner S., Henshaw T., Garrood I., Giunti P., Hedderly T., Abiona A., Naik H., Harrop G., McGibbon D., Jaspers N.G.J., Botta E., Nardo T., Stefanini M., Young A.R., Sarkany R.P.E., Lehmann A.R. Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect. Proc. Natl. Acad. Sci. U.S.A. 113:E1236-E1245(2016)
Encyclopedic resources	Wikidata; Q98135546
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	7