Cellosaurus cell line 172MA (CVCL

Cross-references
Cell line name	172MA
Synonyms	172 MAnchester
Accession	CVCL_ZU22
Resource Identification Initiative	To cite this cell line use: 172MA (RRID:CVCL_ZU22)
Comments	Senescence: Senesces at 26 PDL (PubMed=9649131). Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg337Cys (c.1009C>T); ClinVar=VCV000142536; Zygosity=Hemizygous (PubMed=9649131).
Disease	Li-Fraumeni syndrome (NCIt: C3476) Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	34Y
Category	Finite cell line
Publications	PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396 Boyle J.M., Mitchell E.L.D., Greaves M.J., Roberts S.A., Tricker K., Burt E., Varley J.M., Birch J.M., Scott D. Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families. Br. J. Cancer 77:2181-2192(1998)
Encyclopedic resources	Wikidata; Q98125302
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	8