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Cellosaurus XP1DU LCL (CVCL_ZS43)

[Text version]
Cell line name XP1DU LCL
Synonyms Xeroderma Pigmentosum 1 DUndee LCL; LB103; 103
Accession CVCL_ZS43
Resource Identification Initiative To cite this cell line use: XP1DU LCL (RRID:CVCL_ZS43)
Comments Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:3434; ERCC2; Simple; p.Arg616Trp (c.1846C>T); ClinVar=VCV000016788; Zygosity=Heterozygous (from autologous cell line XP1DU).
  • Mutation; HGNC; HGNC:3434; ERCC2; Simple; p.Arg683Trp (c.2047C>T); ClinVar=VCV000016793; Zygosity=Heterozygous (from autologous cell line XP1DU).
Disease Xeroderma pigmentosum, complementation group D (NCIt: C3967)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZN31 ! XP1DU
Sex of cell Female
Category Transformed cell line
Publications

PubMed=1372096; DOI=10.1016/0921-8777(92)90074-d
Arlett C.F., Harcourt S.A., Cole J., Green M.H.L., Anstey A.V.
A comparison of the response of unstimulated and stimulated T-lymphocytes and fibroblasts from normal, xeroderma pigmentosum and trichothiodystrophy donors to the lethal action of UV-C.
Mutat. Res. 273:127-135(1992)

Cross-references
Encyclopedic resources Wikidata; Q98135416
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number9