Cellosaurus cell line XP2OS(SV)neo (CVCL

Cellosaurus XP2OS(SV)neo (CVCL_ZR65)

[Text version]

Cell line name

XP2OS(SV)neo

Accession

CVCL_ZR65

Resource Identification Initiative

To cite this cell line use: XP2OS(SV)neo (RRID:CVCL_ZR65)

Comments

Population: Japanese.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; 12814; XPA; Simple; c.390-1G>C (IVS3-1G>C); ClinVar=VCV000264684; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).

Disease

Xeroderma pigmentosum, complementation group A (NCIt: C3965)
Xeroderma pigmentosum (ORDO: Orphanet_910)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_3242 (XP2OS(SV))
Children:

CVCL_ZR66 (PX1)

Sex of cell

Female

Age at sampling