ID   XP2OS SV40-transformed
AC   CVCL_ZN80
SY   XP2OS (SV40); GM04312; GM4312; GM04312A; GM4312A; GM04312B
DR   CLO; CLO_0019549
DR   Coriell; GM04312
DR   Wikidata; Q98135659
RX   CelloPub=CLPUB00447;
RX   PubMed=6684957;
RX   PubMed=7519740;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:12814; XPA; Simple; c.390-1G>C (IVS3-1G>C); ClinVar=VCV000264684; Zygosity=Homozygous; Note=Splice acceptor mutation (Coriell=GM04312).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Caution: Could be identical to XP2OS(SV) (Cellosaurus=CVCL_3242).
CC   Misspelling: XP20S (SV40); PubMed=6684957.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C3965; Xeroderma pigmentosum, complementation group A
DI   ORDO; Orphanet_910; Xeroderma pigmentosum
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_F510 ! XP2OS
SX   Female
AG   7Y
CA   Transformed cell line
DT   Created: 02-07-20; Last updated: 19-12-24; Version: 11
CH   CVCL_F509 ! GM15876
//
RX   CelloPub=CLPUB00447;
RA   Mulivor, Richard A.
RA   Suchy, Sharon F.
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992).
//
RX   PubMed=6684957; DOI=10.1007/BF01172877;
RA   Kuhnlein, Urs
RA   Tsang, Siu Sing
RA   Lokken, Opal
RA   Tong, Silvian
RA   Twa, Daniel
RT   "Cell lines from xeroderma pigmentosum complementation group A lack a
RT   single-stranded-DNA-binding activity.";
RL   Biosci. Rep. 3:667-674(1983).
//
RX   PubMed=7519740; DOI=10.1016/0165-7992(94)90014-0;
RA   Jones, Christopher J.
RA   Lloyd, R. Stephen
RA   Wood, Richard Dean
RT   "Analysis of cells harboring a putative DNA repair gene reveals a lack
RT   of evidence for a second independent xeroderma pigmentosum group A
RT   correcting gene.";
RL   Mutat. Res. 324:159-164(1994).
//