Cellosaurus cell line XP26VI (CVCL

Cellosaurus XP26VI (CVCL_ZN45)

Cross-references
Cell line name	XP26VI
Synonyms	Xeroderma Pigmentosum 26 VIllejuif
Accession	CVCL_ZN45
Resource Identification Initiative	To cite this cell line use: XP26VI (RRID:CVCL_ZN45)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:3434; ERCC2; Simple; p.Arg616Pro (c.1847G>C); ClinVar=VCV000329508; Zygosity=Heterozygous (PubMed=9238033). Mutation; HGNC; HGNC:3434; ERCC2; Simple; p.Arg683Trp (c.2047C>T); ClinVar=VCV000016793; Zygosity=Heterozygous (PubMed=9238033).
Disease	Xeroderma pigmentosum, complementation group D (NCIt: C3967) Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	15Y
Category	Finite cell line
Publications	PubMed=9238033; DOI=10.1073/pnas.94.16.8658; PMCID=PMC23065 Taylor E.M., Broughton B.C., Botta E., Stefanini M., Sarasin A., Jaspers N.G.J., Fawcett H., Harcourt S.A., Arlett C.F., Lehmann A.R. Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene. Proc. Natl. Acad. Sci. U.S.A. 94:8658-8663(1997) PubMed=14688028; DOI=10.1093/carcin/bgh046 Arbault S., Sojic N., Bruce D., Amatore C., Sarasin A., Vuillaume M. Oxidative stress in cancer prone xeroderma pigmentosum fibroblasts Real-time and single cell monitoring of superoxide and nitric oxide production with microelectrodes. Carcinogenesis 25:509-515(2004)
Encyclopedic resources	Wikidata; Q98135608
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	8