Cellosaurus cell line DUT (CVCL

Cellosaurus DUT (CVCL_ZI16)

[Text version]

Cell line name

DUT

Accession

CVCL_ZI16

Resource Identification Initiative

To cite this cell line use: DUT (RRID:CVCL_ZI16)

Comments

Population: African; Kenyan.
Selected for resistance to: ChEBI; CHEBI:472805; Ouabain.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.

Sequence variations

Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line).
Mutation; HGNC; 914; B2M; Simple; p.Met1Ile (c.3G>C); Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 2514; CTNNB1; Simple; p.Ala5_Ala80del (c.14_241del228); Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (from parent cell line).

Disease

EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0008 (Daudi)
Children:

CVCL_6217 (DUTKO-1)

Sex of cell

Male

Age at sampling

16Y