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Cellosaurus PICAT (CVCL_ZI14)

[Text version]
Cell line name PICAT
Accession CVCL_ZI14
Resource Identification Initiative To cite this cell line use: PICAT (RRID:CVCL_ZI14)
Comments Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI:17698; Chloramphenicol.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr163His (c.487T>C); ClinVar=VCV000376680; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2676 (P3HR-1)
Children:
CVCL_ZI15 (PICATPO-1)CVCL_6218 (RUDPICAT-1)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=6278187; DOI=10.1093/jnci/68.2.179
Zeuthen J., Klein G., Ber R., Masucci G., Bisballe S., Povey S., Terasaki P.I., Ralph P.
Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. I Isolation, characterization, cell surface markers, and B-cell markers.
J. Natl. Cancer Inst. 68:179-195(1982)

PubMed=6278188; DOI=10.1093/jnci/68.2.197
Klein G., Zeuthen J., Ber R., Ernberg I.
Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. II Epstein-Barr virus induction patterns.
J. Natl. Cancer Inst. 68:197-202(1982)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZI14
Encyclopedic resources Wikidata; Q98128587
Entry history
Entry creation02-Jul-2020
Last entry update02-May-2024
Version number8