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Cellosaurus HEK293 Flp-In T-Rex GLUT1_P485L (CVCL_ZI11)

[Text version]
Cell line name HEK293 Flp-In T-Rex GLUT1_P485L
Accession CVCL_ZI11
Resource Identification Initiative To cite this cell line use: HEK293 Flp-In T-Rex GLUT1_P485L (RRID:CVCL_ZI11)
Comments Characteristics: Transfected with a BirA-FLAG-SLC2A1(P485L) construct.
Genetic integration: Method=Transfection; Gene=HGNC; 11005; SLC2A1 (Note=With p.Pro485Leu).
Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U427 (Flp-In-T-REx-293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=30197081; DOI=10.1016/j.cell.2018.08.019
Meyer K., Kirchner M., Uyar B., Cheng J.-Y., Russo G., Hernandez-Miranda L.R., Szymborska A., Zauber H., Rudolph I.-M., Willnow T.E., Akalin A., Haucke V., Gerhardt H., Birchmeier-Kohler C., Kuhn R., Krauss M., Diecke S., Pascual J.M., Selbach M.
Mutations in disordered regions can cause disease by creating dileucine motifs.
Cell 175:239-253.e17(2018)

Cross-references
Encyclopedic resources Wikidata; Q98126664
Entry history
Entry creation02-Jul-2020
Last entry update10-Sep-2024
Version number6