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Cellosaurus CLC3 (CVCL_ZF90)

[Text version]
Cell line name CLC3
Synonyms Chinese Liver Cancer cell line 3
Accession CVCL_ZF90
Resource Identification Initiative To cite this cell line use: CLC3 (RRID:CVCL_ZF90)
Comments Part of: Liver Cancer Model Repository (LIMORE).
Population: Chinese.
Doubling time: 17.72 hours (PubMed=31378681).
Omics: Genome sequenced.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Pro865Glnfs*50 (c.2594_2597delCAGC); Zygosity=Unspecified (PubMed=31378681).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31378681).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Ile (c.839G>T); ClinVar=VCV000161517; Zygosity=Unspecified (PubMed=31378681).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 77Y
Category Cancer cell line
STR profile Source(s): PubMed=31378681

Markers:
AmelogeninX
CSF1PO10,11
D5S8189,10
D7S82011
D13S31712
D16S53912
TH019
TPOX8,11
vWA16,18

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Publications

PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724
Qiu Z.-X., Li H., Zhang Z.-T., Zhu Z.-F., He S., Wang X.-J., Wang P.-C., Qin J.-J., Zhuang L.-P., Wang W., Xie F.-B., Gu Y., Zou K.-K., Li C., Li C., Wang C.-H., Cen J., Chen X.-T., Shu Y.-J., Zhang Z., Sun L.-L., Min L.-H., Fu Y., Huang X.-W., Lv H., Zhou H., Ji Y., Zhang Z.-G., Meng Z.-Q., Shi X.-L., Zhang H.-B., Li Y.-X., Hui L.-J.
A pharmacogenomic landscape in human liver cancers.
Cancer Cell 36:179-193.e11(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZF90
LIMORE; CLC3
Encyclopedic resources Wikidata; Q98125652
Gene expression databases GEO; GSM2551559
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number10