ID   RB522
AC   CVCL_ZF04
DR   Wikidata; Q98128832
RX   PubMed=23498719;
RX   PubMed=30584916;
RX   PubMed=32123578;
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; None_reported; -; Zygosity=- (PubMed=30584916).
DI   NCIt; C7541; Retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 19-12-24; Version: 6
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RX   PubMed=23498719; DOI=10.1016/S1470-2045(13)70045-7;
RA   Rushlow D.E., Mol B.M., Kennett J.Y., Yee S., Pajovic S.,
RA   Theriault B.L., Prigoda-Lee N.L., Spencer C., Dimaras H., Corson T.W.,
RA   Pang R., Massey C., Godbout R., Jiang Z., Zacksenhaus E., Paton K.,
RA   Moll A.C., Houdayer C., Raizis A., Halliday W., Lam W.L.,
RA   Boutros P.C., Lohmann D.R., Dorsman J.C., Gallie B.L.;
RT   "Characterisation of retinoblastomas without RB1 mutations: genomic,
RT   gene expression, and clinical studies.";
RL   Lancet Oncol. 14:327-334(2013).
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RX   PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018;
RA   Schwermer M., Hiber M., Dreesmann S., Rieb A., Theissen J., Herold T.,
RA   Schramm A., Temming P., Steenpass L.;
RT   "Comprehensive characterization of RB1 mutant and MYCN amplified
RT   retinoblastoma cell lines.";
RL   Exp. Cell Res. 375:92-99(2019).
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RX   PubMed=32123578; DOI=10.1038/s41420-020-0237-8; PMCID=PMC7026052;
RA   Aubry A., Yu T., Bremner R.;
RT   "Preclinical studies reveal MLN4924 is a promising new retinoblastoma
RT   therapy.";
RL   Cell Death Discov. 6:2.1-2.12(2020).
//