ID   NKc21
AC   CVCL_ZE33
DR   Wikidata; Q98127919
RX   PubMed=20977447;
RX   PubMed=28765827;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 02-07-20; Last updated: 10-09-24; Version: 8
//
RX   PubMed=20977447; DOI=10.1111/j.1365-2133.2010.10092.x;
RA   Chamcheu J.C., Pihl-Lundin I., Eteti Mouyobo C., Gester T., Virtanen M.,
RA   Moustakas A., Navsaria H.A., Vahlquist A., Torma H.;
RT   "Immortalized keratinocytes derived from patients with epidermolytic
RT   ichthyosis reproduce the disease phenotype: a useful in vitro model
RT   for testing new treatments.";
RL   Br. J. Dermatol. 164:263-272(2011).
//
RX   PubMed=28765827; DOI=10.1016/j.omtm.2017.06.008; PMCID=PMC5527154;
RA   Aushev M., Koller U., Mussolino C., Cathomen T., Reichelt J.;
RT   "Traceless targeting and isolation of gene-edited immortalized
RT   keratinocytes from epidermolysis bullosa simplex patients.";
RL   Mol. Ther. Methods Clin. Dev. 6:112-123(2017).
//