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Cellosaurus EB11 (CVCL_ZE28)

[Text version]
Cell line name EB11
Accession CVCL_ZE28
Resource Identification Initiative To cite this cell line use: EB11 (RRID:CVCL_ZE28)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
Disease Epidermolysis bullosa simplex (NCIt: C84692)
Epidermolysis bullosa simplex, generalized severe (ORDO: Orphanet_79396)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZE29 ! EB12
CVCL_UJ78 ! MLi002-A
Sex of cell Female
Age at sampling 38Y
Category Transformed cell line
Publications

PubMed=21490615; DOI=10.1038/jid.2011.93
Chamcheu J.C., Navsaria H.A., Pihl-Lundin I., Liovic M., Vahlquist A., Torma H.
Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases.
J. Invest. Dermatol. 131:1684-1691(2011)

PubMed=28765827; DOI=10.1016/j.omtm.2017.06.008; PMCID=PMC5527154
Aushev M., Koller U., Mussolino C., Cathomen T., Reichelt J.
Traceless targeting and isolation of gene-edited immortalized keratinocytes from epidermolysis bullosa simplex patients.
Mol. Ther. Methods Clin. Dev. 6:112-123(2017)

Cross-references
Encyclopedic resources Wikidata; Q98125932
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number10