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Cellosaurus A2780-CBDCA-R (CVCL_ZE22)

[Text version]
Cell line name A2780-CBDCA-R
Synonyms CBDCA-R-A2780
Accession CVCL_ZE22
Resource Identification Initiative To cite this cell line use: A2780-CBDCA-R (RRID:CVCL_ZE22)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI_31355; Carboplatin (CBP; Paraplatin).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=30894224; DOI=10.1186/s40659-019-0220-0; PMCID=PMC6427839
Viscarra T., Buchegger K., Jofre I.A., Riquelme I., Zanella L., Abanto Marin M., Parker A.C., Piccolo S.R., Roa J.C., Ili C.G., Brebi P.
Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line.
Biol. Res. 52:13.1-13.13(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZE22
Encyclopedic resources Wikidata; Q98125441
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7