ID   1321N1-HA-P2Y1
DR   Kerafast; ENC018
DR   Wikidata; Q98125085
RX   PubMed=8733591;
CC   Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 8539; P2RY1 (with a N-terminal HA tag).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from sampling site: Brain.
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0110 ! 1321N1
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 21-03-23; Version: 6
RX   PubMed=8733591; DOI=10.1111/j.1476-5381.1996.tb15381.x;
RA   Schachter J.B., Li Q., Boyer J.L., Nicholas R.A., Harden T.K.;
RT   "Second messenger cascade specificity and pharmacological selectivity
RT   of the human P2Y1-purinoceptor.";
RL   Br. J. Pharmacol. 118:167-173(1996).