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Cellosaurus NIH 3T3 Met-V1186L (CVCL_ZD75)

[Text version]
Cell line name NIH 3T3 Met-V1186L
Synonyms Murine MET (V1206L) Expressing NIH3T3 Cell Line
Accession CVCL_ZD75
Resource Identification Initiative To cite this cell line use: NIH 3T3 Met-V1186L (RRID:CVCL_ZD75)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:96969; Met (Note=With p.Val1186Leu).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=9326629; DOI=10.1073/pnas.94.21.11445; PMCID=PMC23495
Jeffers M., Schmidt L.S., Nakaigawa N., Webb C.P., Weirich G., Kishida T., Zbar B., Vande Woude G.F. Jr.
Activating mutations for the met tyrosine kinase receptor in human cancer.
Proc. Natl. Acad. Sci. U.S.A. 94:11445-11450(1997)

PubMed=10327054; DOI=10.1038/sj.onc.1202547
Schmidt L.S., Junker K., Nakaigawa N., Kinjerski T., Weirich G., Miller M., Lubensky I.A., Neumann H.P.H., Brauch H., Decker J., Vocke C.D., Brown J.A., Jenkins R.B., Richard S., Bergerheim U.S.R., Gerrard B., Dean M., Linehan W.M., Zbar B.
Novel mutations of the MET proto-oncogene in papillary renal carcinomas.
Oncogene 18:2343-2350(1999)

Cross-references
Cell line collections (Providers) Kerafast; ENH029-FP
Encyclopedic resources Wikidata; Q98127849
Entry history
Entry creation02-Jul-2020
Last entry update10-Sep-2024
Version number6