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Cellosaurus MLEC-Sulf1-/-;Sulf2-/- (CVCL_ZD31)

[Text version]
Cell line name MLEC-Sulf1-/-;Sulf2-/-
Synonyms Mouse Lung Endothelial Sulf1-/-;Sulf2-/-
Accession CVCL_ZD31
Resource Identification Initiative To cite this cell line use: MLEC-Sulf1-/-;Sulf2-/- (RRID:CVCL_ZD31)
Comments Knockout cell: Method=Floxing/Cre recombination; MGI; MGI:2138563; Sulf1.
Knockout cell: Method=Floxing/Cre recombination; MGI; MGI:1919293; Sulf2.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Endothelial cell of lung; CL=CL_1001567.
Breed/subspecies: Sulf1f/f;Sulf2f/f x C57BL/6J.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_ZD30 (MLEC-Sulf1f/f;Sulf2f/f)
Sex of cell Sex unspecified
Age at sampling 8-10W
Category Transformed cell line
Publications

PubMed=30377379; DOI=10.1038/s41592-018-0189-6; PMCID=PMC6214364
Qiu H., Shi S.-S., Yue J.-W., Xin M., Nairn A.V., Lin L., Liu X., Li G., Archer-Hartmann S.A., Dela Rosa M., Galizzi M., Wang S.-C., Zhang F., Azadi P., van Kuppevelt T.H., Cardoso W.V., Kimata K., Ai X.-B., Moremen K.W., Esko J.D., Linhardt R.J., Wang L.-C.
A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Nat. Methods 15:889-899(2018)

Cross-references
Cell line collections (Providers) Kerafast; EGA371
Encyclopedic resources Wikidata; Q98127269
Entry history
Entry creation02-Jul-2020
Last entry update10-Sep-2024
Version number8